Before visiting St. Louis, understand that public transportation is virtually nonexistent. And while not a huge city, it’s much too spread out to walk comfortably from place to place. Unless you’re willing to ride an Uber every day, having a car is a must.
As you’ll need a car to get around regardless, location is not incredibly important as long as you’re somewhere relatively central. In addition to a myriad of hotels, there are plenty of Airbnb options as well, which is oftentimes the better value.
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